Many translated example sentences containing "peak plasma concentration" preferably based on area under the curve (AUC) data, or peak concentration (C

7 Feb 2016 The area under the plasma (serum, or blood) concentration versus time curve ( AUC) has an number of important uses in toxicology,

The plasma [Fluorine sup -]-time curve after a brief exposure to sevoflurane (0.82 minimum alveolar concentration *symbol* h [MAC *symbol* h]) in infants and children yielded a low peak fluoride value, 13.0+/-3.6 micro Meter, but postoperative measurements were discontinued after only 4 h. 2014-02-05 · ROC curves for blood loss versus fibrinogen concentration and MCF showed that a plasma fibrinogen concentration of 1.5 g l −1 and a MCF value 3 mm or less could be used to predict blood loss. CONCLUSION . Post-CPB plasma fibrinogen concentration significantly influences blood loss in children undergoing cardiac surgery. Traductions en contexte de "plasma concentration curve" en anglais-français avec Reverso Context : Area under the plasma concentration curve (AUC) of ertapenem in adults increases nearly dose- proportionally over the 0.5 to 2 g dose range. Area Under the plasma-concentration curve is abbreviated as AUC. related. The list of abbreviations related to AUC - Area Under the plasma-concentration curve.

Plasma concentration curve

Description. The area under the plasma drug concentration-time curve (AUC) reflects the actual body exposure to drug after administration of a dose of the drug and is expressed in mg*h/L. This area under the curve is dependant on the rate of elimination of the drug from the body and the dose administered. The total amount of drug eliminated by the body may be assessed by adding up or integrating the amounts eliminated in each time interval, from time zero (time of the administration of the If we plot a graph between plasma conc. vs time after oral administration of a drug, then we will get the plasma concentration vs time curve. There are 3 imp The plasma level time curve is plotted after measured drug concentration in plasma of an animal at different time intervals.

1.

23 Feb 2006 The time taken for the plasma concentration of a drug to fall by 50% when first- order kinetics are Area under plasma concentration-time curve.

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The mechanisms that determine this plasma-concentration profile ( absorption, distribution, metabolism and excretion) are characterized by pharmacokinetic parameters. Diseases, drug interactions, physiological or genetic variations may influence these parameters in a given individual.”

b.w. body weight.

– Maximum concentration (Cmax),.
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Plasma concentrations of rabeprazole was measured by an HPLC-assay (l.l.q.=1 ng/ml).
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23 Feb 2006 The time taken for the plasma concentration of a drug to fall by 50% when first- order kinetics are Area under plasma concentration-time curve.

mg=K * (mg The plasma concentration-time curve (blood level curve) is the focal point of bioavailability assessment and is obtain when serial blood samples are taken after drug administration and analyzed for drug concentration A typical blood level curve obtained after oral administration of a drug is as follows:- to the right andapproximates to the concentration-effect curve following intravenous injection. As shown by Figure 6, the theoretical curve is in close agreement with the concentration-effect curve obtainedafterbothintravenous andoral administra-tion. In a comparison of plasma concentration and effect, the correlation for the combinedparentdrug Where C is the concentration at time (t); C i is the respective exponential coefficient; -λ i is the respective exponential constant 2 - Calculation of area under the plasma level versus time curve (AUC) combinations of two compounds, the tumor static concentration curve. The TSC value of a single compound is the plasma concentration of that compound required to maintain the tumor in stasis. Such values have been obtained for TGI models ( 12,32). The TSC curve is a generalization of the TSC value when two compounds are given together ( 33,34). Plasma concentrations of rabeprazole was measured by an HPLC-assay (l.l.q.=1 ng/ml).

If we plot a graph between plasma conc. vs time after oral administration of a drug, then we will get the plasma concentration vs time curve. There are 3 imp

A nonangular continuous bend or line. 2. A chart or graphic representation, by means of a continuous line connecting individual observations, of the course of a physiologic activity, of the number of cases of a disease in a given period, or of any entity that might be otherwise presented by a table of figures. The plasma concentration-time curves of lumefantrine on linear (Figure) and log scale were used to calculate the variety of pharmacokinetic parameters (Table) There was a significant correlation between level of CYP2E1 mRNA in mononuclear cells and the area under the plasma concentration-time curve of plasma inorganic fluoride from the beginning of sevoflurane administration to infinity in uninduced and uninhibited patients (r2 = 0.56; P < 0.01). Results: During itraconazole treatment, or 4 days after, alpha-hydroxymetabolite the dose-corrected area under the plasma midazolam concentration time curve (AUC0-infinity) was 8- or 2.6-fold larger than that before itraconazole (i.e.

The area under the plasma concentration–time curve (AUC) increased Area Under the Plasma Concentration-Time Curve From Time Zero to the Last Quantifiable Concentration (AUC 0-t) of Evobrutinib, Pre-dose up to 30 hours Area under the plasma concentration curve (AUC0-∞ ) of 50mg [14C]-SHP626 and RAD extrapolated to infinity, calculated using the observed value of the last Many translated example sentences containing "peak plasma concentration" preferably based on area under the curve (AUC) data, or peak concentration (C then it calculates and draws the plasma concentration curve. The basis for the simulation is a one-compartment model with first-order elimination kinetics.